Search on: T4-ENDONUCLEASE II 
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Descriptor English:   Deoxyribonuclease I 
Descriptor Spanish:   Desoxirribonucleasa I 
Descriptor Portuguese:   Desoxirribonuclease I 
Synonyms English:   DNA Endonuclease
DNA Nicking Enzyme
DNAase I
Dornavac
Endonuclease I
Nickase
Pancreatic DNase
T4-Endonuclease II
T7-Endonuclease I
Thymonuclease
DNase, Pancreatic
Endonuclease, DNA
T4 Endonuclease II
T7 Endonuclease I
DNase I
Streptodornase  
Tree Number:   D08.811.277.352.335.350.250
Definition English:   An enzyme capable of hydrolyzing highly polymerized DNA by splitting phosphodiester linkages, preferentially adjacent to a pyrimidine nucleotide. This catalyzes endonucleolytic cleavage of DNA yielding 5'-phosphodi- and oligonucleotide end-products. The enzyme has a preference for double-stranded DNA. 
Indexing Annotation English:   do not confuse X ref STREPTODORNASE with STREPTODORNASE AND STREPTOKINASE: see note there; DF: note short X ref
History Note English:   85; STREPTODORNASE was see DEOXYRIBONUCLEASES 1966-93 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   3873 
Unique Identifier:   D003850 

Occurrence in VHL:
 

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